Hartman Institute for Therapeutic Organ Regeneration
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2018
Mercer EJ, Lin Y-F, Cohen-Gould L, Evans T.  2018.  Hspb7 is a cardioprotective chaperone facilitating sarcomeric proteostasis.. Dev Biol. 435(1):41-55.
Durán JGabriel Ba, Lis R, Lu TM, Rafii S.  2018.  In vitro conversion of adult murine endothelial cells to hematopoietic stem cells.. Nat Protoc. 13(12):2758-2780.
Rafii S, Palikuqi B.  2018.  Isolation and Characterization of Mouse Organ-Specific Endothelial Transcriptomes.. Methods Mol Biol. 1846:301-308.
Merna N, Wong AK, Barahona V, Llanos P, Kunar B, Palikuqi B, Ginsberg M, Rafii S, Rabbany SY.  2018.  Laminar shear stress modulates endothelial luminal surface stiffness in a tissue-specific manner.. Microcirculation. 25(5):e12455.
Robinson CL, Chong ACN, Ashbrook AW, Jeng G, Jin J, Chen H, Tang EI, Martin LA, Kim RS, Kenyon RM et al..  2018.  Male germ cells support long-term propagation of Zika virus.. Nat Commun. 9(1):2090.
Zhou Q, Melton DA.  2018.  Pancreas regeneration.. Nature. 557(7705):351-358.
Finley LWS, Vardhana SA, Carey BW, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S et al..  2018.  Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.. Nat Cell Biol. 20(5):565-574.
Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P et al..  2018.  Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.. Sci Immunol. 3(19)
Ghazizadeh Z, Fattahi F, Mirzaei M, Bayersaikhan D, Lee J, Chae S, Hwang D, Byun K, Tabar MSharifi, Taleahmad S et al..  2018.  Prospective Isolation of ISL1 Cardiac Progenitors from Human ESCs for Myocardial Infarction Therapy.. Stem Cell Reports. 10(3):848-859.
Yokoyama M, Rafii S.  2018.  Setting up the dermis for scar-free healing.. Nat Cell Biol. 20(4):365-366.
Bhang DHa, Kim B-J, Kim BGak, Schadler K, Baek K-H, Kim YHee, Hsiao W, Ding B-S, Rafii S, Weiss MJ et al..  2018.  Testicular endothelial cells are a critical population in the germline stem cell niche.. Nat Commun. 9(1):4379.
Reichman DE, Park L, Man L, Redmond D, Chao K, Harvey RP, Taketo MM, Rosenwaks Z, James D.  2018.  Wnt inhibition promotes vascular specification of embryonic cardiac progenitors.. Development. 145(1)
2019
Kumar R, Evans T.  2019.  Activation-Induced Cytidine Deaminase Regulates Fibroblast Growth Factor/Extracellular Signal-Regulated Kinases Signaling to Achieve the Naïve Pluripotent State During Reprogramming.. Stem Cells. 37(8):1003-1017.
Hoarau-Véchot J, Touboul C, Halabi N, Blot-Dupin M, Lis R, Khalil CAbi, Rafii S, Rafii A, Pasquier J.  2019.  Akt-activated endothelium promotes ovarian cancer proliferation through notch activation.. J Transl Med. 17(1):194.
Fernando TM, Marullo R, Gresely BPera, Phillip JM, Yang SNing, Lundell-Smith G, Torregroza I, Ahn H, Evans T, Győrffy B et al..  2019.  BCL6 Evolved to Enable Stress Tolerance in Vertebrates and Is Broadly Required by Cancer Cells to Adapt to Stress.. Cancer Discov. 9(5):662-679.
Gravotta D, Bay APerez, Jonker CTH, Zager PJ, Benedicto I, Schreiner R, Caceres PS, Rodriguez-Boulan E.  2019.  Clathrin and clathrin adaptor AP-1 control apical trafficking of megalin in the biosynthetic and recycling routes.. Mol Biol Cell. 30(14):1716-1728.
Badieyan ZSadat, Evans T.  2019.  Concise Review: Application of Chemically Modified mRNA in Cell Fate Conversion and Tissue Engineering.. Stem Cells Transl Med. 8(8):833-843.
Cook B, Rafiq R, Lee H, Banks KM, El-Debs M, Chiaravalli J, J Glickman F, Das BC, Chen S, Evans T.  2019.  Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-β.. Cell Chem Biol. 26(7):926-935.e6.
Lan Y, Evans T.  2019.  Epigenetic Regulation of Cardiac Development and Disease through DNA Methylation.. J Life Sci (Westlake Village). 1(2):1-10.
Ma J, Redmond D, Miyaguchi A, Nam AS, Nie K, Mathew S, Elemento O, Tam W.  2019.  Exploring tumor clonal evolution in bone marrow of patients with diffuse large B-cell lymphoma by deep IGH sequencing and its potential relevance in relapse.. Blood Cancer J. 9(9):69.
Li QV, Dixon G, Verma N, Rosen BP, Gordillo M, Luo R, Xu C, Wang Q, Soh C-L, Yang D et al..  2019.  Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation.. Nat Genet. 51(6):999-1010.
Durán JGabriel Ba, Lis R, Rafii S.  2019.  Haematopoietic stem cell reprogramming and the hope for a universal blood product.. FEBS Lett. 593(23):3253-3265.
Khalil DN, Suek N, Campesato LFelipe, Budhu S, Redmond D, Samstein RM, Krishna C, Panageas KS, Capanu M, Houghton S et al..  2019.  In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors.. J Clin Invest. 129(8):3435-3447.
Jaffré F, Miller CL, Schänzer A, Evans T, Roberts AE, Hahn A, Kontaridis MI.  2019.  Inducible Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Aberrant Extracellular Regulated Kinase 5 and Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Concomitantly Promote Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome.. Circulation. 140(3):207-224.
Barry DM, McMillan EA, Kunar B, Lis R, Zhang T, Lu T, Daniel E, Yokoyama M, Gomez-Salinero JM, Sureshbabu A et al..  2019.  Molecular determinants of nephron vascular specialization in the kidney.. Nat Commun. 10(1):5705.