Hartman Institute for Therapeutic Organ Regeneration


dopamine neuron senescence after COVID infection

A new study reported that SARS-CoV-2, the virus that causes COVID, can infect dopamine neurons in the brain and trigger senescence—when a cell loses the ability to grow and divide. The researchers from Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and Columbia University Vagelos College of Physicians and Surgeons suggest that further research on this finding may shed light on the neurological symptoms associated with long COVID such as brain fog, lethargy and depression....

Cells labeled in pink and blue in pancreatic cancer organoid

A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell Medicine.

In the study, published Dec. 26 in Cell Stem Cell, the scientists tested more than 6,000 compounds on their pancreatic tumor organoids, which contain a common pancreatic cancer...

islet cell labeled with green for insulin and blue for nucleus

A drug currently in clinical trials as a cancer therapy can also stimulate pancreatic beta cells to secrete insulin, revealing a previously unknown mechanism for insulin regulation in type 2 diabetes, according to a new study by Weill Cornell Medicine investigators. The preclinical discovery, reported Nov. 9 in Nature Chemical Biology, provides a new chemical tool for probing the biology of diabetes, and...

immunofluorescent image of differentiated pancreatic beta cells

In experiments of unprecedented scale, investigators at Weill Cornell Medicine and the National Institutes of Health have revealed new aspects of the complex genetics behind Type 2 diabetes. Through these discoveries, and by providing a template for future studies, this research furthers efforts to better understand, and ultimately, treat this common metabolic disease.

Previous studies have generally examined the influence of individual genes. In...

Two men holding a big check for their cash prize of $80,000

Standing on the stage at Uris Auditorium on June 1, Dr. Joe Zhou, an associate professor in regenerative medicine in medicine at Weill Cornell Medicine, made the case for the necessity of developing new approaches to treat diabetes, a disease he called “a true epidemic of the modern world.”

More than 400 million...

microscopic image

Stem cells from the human stomach can be converted into cells that secrete insulin in response to rising blood sugar levels, offering a promising approach to treating diabetes, according to a preclinical study from researchers at Weill Cornell Medicine.

In the study, which appeared April 27 in Nature Cell Biology, the researchers showed that they could take stem cells obtained from human stomach tissue and reprogram them...

stock image of cells

Endothelial cells—the cells that line blood vessels—grown alongside leukemia cells become corrupted and rescue the cancer cells from many chemotherapy drugs, a study by Weill Cornell Medicine investigators found.

A growing body of evidence suggests that genetic mutations are not enough to cause cancer; tumor cells also need the right environment to grow. The new...

Scientific stock image

Two genes working in concert sustain the integrity of healthy blood vessels, Weill Cornell Medicine investigators discovered in new research. The findings could lead to new approaches treating cardiovascular disease or other inflammatory conditions.

The preclinical study, published Oct. 6 in Nature Cardiovascular Research, shows that the transcription factors ERG and FLI1 work together to shepherd the blood...

Couple posing for a photo

With a generous gift of $10 million from Board of Fellows member Alan Hartman and his wife, Kim, Weill Cornell Medicine will establish a multidisciplinary research institute to advance organ regeneration and repair.

The Hartman Institute for Therapeutic Organ Regeneration will expand the frontiers of stem cell-based research and organoid development, creating a hub within Weill Cornell Medicine’s Division of Regenerative Medicine that will facilitate collaboration among researchers,...

Weill Cornell Medicine
Hartman Institute for Therapeutic Organ Regeneration
1300 York Ave, Box 136 New York, NY 10065