Hartman Institute for Therapeutic Organ Regeneration

Publications

Found 30 results
Author Title Type [ Year(Desc)]
Filters: Author is Butler, Jason M  [Clear All Filters]
2008
Shmelkov SV, Butler JM, Hooper AT, Hormigo A, Kushner J, Milde T, St Clair R, Baljevic M, White I, Jin DK et al..  2008.  CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors.. J Clin Invest. 118(6):2111-20.
Seandel M, Butler JM, Kobayashi H, Hooper AT, White IA, Zhang F, Vertes EL, Kobayashi M, Zhang Y, Shmelkov SV et al..  2008.  Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene.. Proc Natl Acad Sci U S A. 105(49):19288-93.
2009
Hooper AT, Butler JM, Nolan DJ, Kranz A, Iida K, Kobayashi M, Kopp H-G, Shido K, Petit I, Yanger K et al..  2009.  Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells.. Cell Stem Cell. 4(3):263-74.
2010
Kobayashi H, Butler JM, O'Donnell R, Kobayashi M, Ding B-S, Bonner B, Chiu VK, Nolan DJ, Shido K, Benjamin L et al..  2010.  Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells.. Nat Cell Biol. 12(11):1046-56.
Butler JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, Seandel M, Shido K, White IA, Kobayashi M et al..  2010.  Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.. Cell Stem Cell. 6(3):251-64.
Ding B-S, Nolan DJ, Butler JM, James D, Babazadeh AO, Rosenwaks Z, Mittal V, Kobayashi H, Shido K, Lyden D et al..  2010.  Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration.. Nature. 468(7321):310-5.
Butler JM, Kobayashi H, Rafii S.  2010.  Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors.. Nat Rev Cancer. 10(2):138-46.
2011
Kimura Y, Ding B, Imai N, Nolan DJ, Butler JM, Rafii S.  2011.  c-Kit-mediated functional positioning of stem cells to their niches is essential for maintenance and regeneration of adult hematopoiesis.. PLoS One. 6(10):e26918.
2012
Butler JM, Gars EJ, James DJ, Nolan DJ, Scandura JM, Rafii S.  2012.  Development of a vascular niche platform for expansion of repopulating human cord blood stem and progenitor cells.. Blood. 120(6):1344-7.
Ginsberg M, James D, Ding B-S, Nolan D, Geng F, Butler JM, Schachterle W, Pulijaal VR, Mathew S, Chasen ST et al..  2012.  Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression.. Cell. 151(3):559-75.
Butler JM, Rafii S.  2012.  Generation of a vascular niche for studying stem cell homeostasis.. Methods Mol Biol. 904:221-33.
2013
Poulos MG, Guo P, Kofler NM, Pinho S, Gutkin MC, Tikhonova A, Aifantis I, Frenette PS, Kitajewski J, Rafii S et al..  2013.  Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis.. Cell Rep. 4(5):1022-34.
Rafii S, Kloss CC, Butler JM, Ginsberg M, Gars E, Lis R, Zhan Q, Josipovic P, Ding B-S, Xiang J et al..  2013.  Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition.. Blood. 121(5):770-80.
Nolan DJ, Ginsberg M, Israely E, Palikuqi B, Poulos MG, James D, Ding B-S, Schachterle W, Liu Y, Rosenwaks Z et al..  2013.  Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration.. Dev Cell. 26(2):204-19.
2014
Poulos MG, Gars EJ, Gutkin MC, Kloss CC, Ginsberg M, Scandura JM, Rafii S, Butler JM.  2014.  Activation of the vascular niche supports leukemic progression and resistance to chemotherapy.. Exp Hematol. 42(11):976-986.e3.
Cao Z, Ding B-S, Guo P, Lee SB, Butler JM, Casey SC, Simons M, Tam W, Felsher DW, Shido K et al..  2014.  Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance.. Cancer Cell. 25(3):350-65.
Sandler VM, Lis R, Liu Y, Kedem A, James D, Elemento O, Butler JM, Scandura JM, Rafii S.  2014.  Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.. Nature. 511(7509):312-8.
2016
Rafii S, Butler JM, Ding B-S.  2016.  Angiocrine functions of organ-specific endothelial cells.. Nature. 529(7586):316-25.
Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG et al..  2016.  Distinct bone marrow blood vessels differentially regulate haematopoiesis.. Nature. 532(7599):323-8.
Poulos MG, Ramalingam P, Gutkin MC, Kleppe M, Ginsberg M, Crowley MJP, Elemento O, Levine RL, Rafii S, Kitajewski J et al..  2016.  Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis.. Nat Commun. 7:13829.
Rafii S, Ginsberg M, Scandura J, Butler JM, Ding B-S.  2016.  Transplantation of Endothelial Cells to Mitigate Acute and Chronic Radiation Injury to Vital Organs.. Radiat Res. 186(2):196-202.
2017
Hadland BK, Varnum-Finney B, Mandal PK, Rossi DJ, Poulos MG, Butler JM, Rafii S, Yoder MC, Yoshimoto M, Bernstein ID.  2017.  A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells.. Stem Cell Reports. 8(6):1563-1572.
Lis R, Karrasch CC, Poulos MG, Kunar B, Redmond D, Duran JGBarcia, Badwe CR, Schachterle W, Ginsberg M, Xiang J et al..  2017.  Conversion of adult endothelium to immunocompetent haematopoietic stem cells.. Nature. 545(7655):439-445.
Gori JL, Butler JM, Kunar B, Poulos MG, Ginsberg M, Nolan DJ, Norgaard ZK, Adair JE, Rafii S, Kiem H-P.  2017.  Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates.. Stem Cells Transl Med. 6(3):864-876.
Guo P, Poulos MG, Palikuqi B, Badwe CR, Lis R, Kunar B, Ding B-S, Rabbany SY, Shido K, Butler JM et al..  2017.  Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression.. J Clin Invest. 127(12):4242-4256.