Hartman Institute for Therapeutic Organ Regeneration

Publications

Found 59 results
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2023
Xue D, Narisu N, D Taylor L, Zhang M, Grenko C, Taylor HJ, Yan T, Tang X, Sinha N, Zhu J et al..  2023.  Functional interrogation of twenty type 2 diabetes-associated genes using isogenic hESC-derived β-like cells.. bioRxiv.
Tang X, Xue D, Zhang T, Nilsson-Payant BE, Carrau L, Duan X, Gordillo M, Tan AY, Qiu Y, Xiang J et al..  2023.  A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection.. Nat Cell Biol. 25(3):381-389.
Tang X, Xue D, Zhang T, Nilsson-Payant BE, Carrau L, Duan X, Gordillo M, Tan AY, Qiu Y, Xiang J et al..  2023.  A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection.. Nat Cell Biol. 25(3):381-389.
Tan L, Duan X, Mutyala P, Zhou T, Amin S, Zhang T, Herbst B, Askan G, Itkin T, Xiang Z et al..  2023.  A targetable pathway to eliminate TRA-1-60+/TRA-1-81+ chemoresistant cancer cells.. J Mol Cell Biol. 15(6)
Itkin T, Houghton S, Schreiner R, Lin Y, Badwe CR, Voisin V, Murison A, Seyedhassantehrani N, Kaufmann KB, Garcia-Prat L et al..  2023.  Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing.. bioRxiv.
Itkin T, Houghton S, Schreiner R, Lin Y, Badwe CR, Voisin V, Murison A, Seyedhassantehrani N, Kaufmann KB, Garcia-Prat L et al..  2023.  Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing.. bioRxiv.
2022
Gomez-Salinero JM, Itkin T, Houghton S, Badwe C, Lin Y, Kalna V, Dufton N, Peghaire CR, Yokoyama M, Wingo M et al..  2022.  Cooperative ETS Transcription Factors Enforce Adult Endothelial Cell Fate and Cardiovascular Homeostasis.. Nat Cardiovasc Res. 1:882-899.
Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai S-Y, Khalaj M, Zhou T, Samuel RM et al..  2022.  A dual knockin hESC reporter line for derivation of human SAN-like cells.. iScience. 25(4):104153.
Guo P, Liu Y, Geng F, Daman AW, Liu X, Zhong L, Ravishankar A, Lis R, Durán JGabriel Ba, Itkin T et al..  2022.  Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability.. Nat Cell Biol. 24(1):99-111.
Han Y, Tan L, Zhou T, Yang L, Carrau L, Lacko LA, Saeed M, Zhu J, Zhao Z, Nilsson-Payant BE et al..  2022.  A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.. Cell Stem Cell. 29(10):1475-1490.e6.
Guo P, Liu Y, Geng F, Daman AW, Liu X, Zhong L, Ravishankar A, Lis R, Durán JGabriel Ba, Itkin T et al..  2022.  Publisher Correction: Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability.. Nat Cell Biol. 24(2):279.
Wan Q, Huang B, Li T, Xiao Y, He Y, Du W, Wang BZ, Dakin GF, Rosenbaum M, Goncalves MD et al..  2022.  Selective targeting of visceral adiposity by polycation nanomedicine.. Nat Nanotechnol. 17(12):1311-1321.
Gomez-Salinero JMaria, Izzo F, Lin Y, Houghton S, Itkin T, Geng F, Bram Y, Adelson RP, Lu TM, Inghirami G et al..  2022.  Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction.. Cell Stem Cell. 29(4):593-609.e7.
2021
Duan X, Tang X, Nair MS, Zhang T, Qiu Y, Zhang W, Wang P, Huang Y, Xiang J, Wang H et al..  2021.  An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection.. Cell Rep. 37(6):109920.
Yang L, Nilsson-Payant BE, Han Y, Jaffré F, Zhu J, Wang P, Zhang T, Redmond D, Houghton S, Møller R et al..  2021.  Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2.. Stem Cell Reports. 16(10):2565.
Yang L, Nilsson-Payant BE, Han Y, Jaffré F, Zhu J, Wang P, Zhang T, Redmond D, Houghton S, Møller R et al..  2021.  Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2.. Stem Cell Reports. 16(9):2274-2288.
Durán JGabriel Ba, Lu T, Houghton S, Geng F, Schreiner R, Xiang J, Rafii S, Redmond D, Lis R.  2021.  Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice.. Commun Biol. 4(1):406.
Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S et al..  2021.  Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.. Nature. 589(7841):270-275.
Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S et al..  2021.  Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.. Nature. 589(7841):270-275.
Yang L, Han Y, Jaffré F, Nilsson-Payant BE, Bram Y, Wang P, Zhu J, Zhang T, Redmond D, Houghton S et al..  2021.  An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts.. Circ Res. 129(1):33-46.
Lu TM, Houghton S, Magdeldin T, Durán JGabriel Ba, Minotti AP, Snead A, Sproul A, Nguyen D-HT, Xiang J, Fine HA et al..  2021.  Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate.. Proc Natl Acad Sci U S A. 118(8)
Tang X, Uhl S, Zhang T, Xue D, Li B, J Vandana J, Acklin JA, Bonnycastle LL, Narisu N, Erdos MR et al..  2021.  SARS-CoV-2 infection induces beta cell transdifferentiation.. Cell Metab. 33(8):1577-1591.e7.
Tang X, Uhl S, Zhang T, Xue D, Li B, J Vandana J, Acklin JA, Bonnycastle LL, Narisu N, Erdos MR et al..  2021.  SARS-CoV-2 infection induces beta cell transdifferentiation.. Cell Metab. 33(8):1577-1591.e7.
2020
Palikuqi B, Nguyen D-HT, Li G, Schreiner R, Pellegata AF, Liu Y, Redmond D, Geng F, Lin Y, Gomez-Salinero JM et al..  2020.  Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis.. Nature. 585(7825):426-432.
Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F et al..  2020.  A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.. Cell Stem Cell. 27(1):125-136.e7.