Hartman Institute for Therapeutic Organ Regeneration
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2018
Zhou Q, Melton DA.  2018.  Pancreas regeneration.. Nature. 557(7705):351-358.
Finley LWS, Vardhana SA, Carey BW, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S et al..  2018.  Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.. Nat Cell Biol. 20(5):565-574.
Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P et al..  2018.  Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.. Sci Immunol. 3(19)
Ghazizadeh Z, Fattahi F, Mirzaei M, Bayersaikhan D, Lee J, Chae S, Hwang D, Byun K, Tabar MSharifi, Taleahmad S et al..  2018.  Prospective Isolation of ISL1 Cardiac Progenitors from Human ESCs for Myocardial Infarction Therapy.. Stem Cell Reports. 10(3):848-859.
Yokoyama M, Rafii S.  2018.  Setting up the dermis for scar-free healing.. Nat Cell Biol. 20(4):365-366.
Bhang DHa, Kim B-J, Kim BGak, Schadler K, Baek K-H, Kim YHee, Hsiao W, Ding B-S, Rafii S, Weiss MJ et al..  2018.  Testicular endothelial cells are a critical population in the germline stem cell niche.. Nat Commun. 9(1):4379.
Reichman DE, Park L, Man L, Redmond D, Chao K, Harvey RP, Taketo MM, Rosenwaks Z, James D.  2018.  Wnt inhibition promotes vascular specification of embryonic cardiac progenitors.. Development. 145(1)
2017
Kedem A, Aelion-Brauer A, Guo P, Wen D, Ding B-S, Lis R, Cheng D, Sandler VM, Rafii S, Rosenwaks Z.  2017.  Activated ovarian endothelial cells promote early follicular development and survival.. J Ovarian Res. 10(1):64.
Lee KSteve, Santagostino SF, Li D, Ramjit A, Serrano K, Ginsberg MD, Ding B-S, Rafii S, Madoff DC.  2017.  Catheter-directed Intraportal Delivery of Endothelial Cell Therapy for Liver Regeneration: A Feasibility Study in a Large-Animal Model of Cirrhosis.. Radiology. 285(1):114-123.
Mendelson K, Pandey S, Hisano Y, Carellini F, Das BC, Hla T, Evans T.  2017.  The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis.. Elife. 6
Pasquier J, Gupta R, Rioult D, Hoarau-Véchot J, Courjaret R, Machaca K, Suwaidi JAl, Stanley EG, Rafii S, Elliott DA et al..  2017.  Coculturing with endothelial cells promotes in vitro maturation and electrical coupling of human embryonic stem cell-derived cardiomyocytes.. J Heart Lung Transplant. 36(6):684-693.
Crespo M, Vilar E, Tsai S-Y, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJoyce, Witherspoon M et al..  2017.  Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.. Nat Med. 23(7):878-884.
Hadland BK, Varnum-Finney B, Mandal PK, Rossi DJ, Poulos MG, Butler JM, Rafii S, Yoder MC, Yoshimoto M, Bernstein ID.  2017.  A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells.. Stem Cell Reports. 8(6):1563-1572.
Benedicto I, Lehmann GL, Ginsberg M, Nolan DJ, Bareja R, Elemento O, Salfati Z, Alam NM, Prusky GT, Llanos P et al..  2017.  Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors.. Nat Commun. 8:15374.
Mercer EJ, Evans T.  2017.  Congenital heart disease in a dish: progress toward understanding patient-specific mutations.. J Thorac Dis. 9(5):E510-E513.
Lis R, Karrasch CC, Poulos MG, Kunar B, Redmond D, Duran JGBarcia, Badwe CR, Schachterle W, Ginsberg M, Xiang J et al..  2017.  Conversion of adult endothelium to immunocompetent haematopoietic stem cells.. Nature. 545(7655):439-445.
Guo P, Rafii S.  2017.  Dangerous Liaisons: Deviant Endothelium NOTCHes toward Tumor Metastasis.. Cancer Cell. 31(3):301-303.
Tsai S-Y, Chen S, Evans T.  2017.  Efficient Generation of Cardiac Purkinje-like Cells from Embryonic Stem Cells by Activating cAMP Signaling.. Curr Protoc Stem Cell Biol. 40:1F.16.1-1F.16.13.
Gori JL, Butler JM, Kunar B, Poulos MG, Ginsberg M, Nolan DJ, Norgaard ZK, Adair JE, Rafii S, Kiem H-P.  2017.  Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates.. Stem Cells Transl Med. 6(3):864-876.
Guo P, Poulos MG, Palikuqi B, Badwe CR, Lis R, Kunar B, Ding B-S, Rabbany SY, Shido K, Butler JM et al..  2017.  Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression.. J Clin Invest. 127(12):4242-4256.
Béguelin W, Rivas MA, Fernández MTCalvo, Teater M, Purwada A, Redmond D, Shen H, Challman MF, Elemento O, Singh A et al..  2017.  EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop.. Nat Commun. 8(1):877.
Shi Z-D, Lee K, Yang D, Amin S, Verma N, Li QV, Zhu Z, Soh C-L, Kumar R, Evans T et al..  2017.  Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development.. Cell Stem Cell. 20(5):675-688.e6.
Zhou T, Tan L, Cederquist GY, Fan Y, Hartley BJ, Mukherjee S, Tomishima M, Brennand KJ, Zhang Q, Schwartz RE et al..  2017.  High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain.. Cell Stem Cell. 21(2):274-283.e5.
Itkin T, Rafii S.  2017.  Leukemic Cells "Gas Up" Leaky Bone Marrow Blood Vessels.. Cancer Cell. 32(3):276-278.
Tchieu J, Zimmer B, Fattahi F, Amin S, Zeltner N, Chen S, Studer L.  2017.  A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages.. Cell Stem Cell. 21(3):399-410.e7.