| Title | VEGF-B Improves Metabolic Health through Vascular Pruning of Fat. |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Rafii S, Carmeliet P |
| Journal | Cell Metab |
| Volume | 23 |
| Issue | 4 |
| Pagination | 571-3 |
| Date Published | 2016 Apr 12 |
| ISSN | 1932-7420 |
| Keywords | Humans, Insulin Resistance, Obesity, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factor B, Vascular Endothelial Growth Factor Receptor-2 |
| Abstract | <p>Unraveling the mechanism VEGF-receptors modulating metabolism has therapeutic implications. In this issue, Robciuc et al. (2016) demonstrate that VEGF-B, by displacing VEGF-A from VEGFR1 and activating VEGFR2, increases adipose tissue vascularity, improves insulin sensitivity, diminishes obesity, and alleviates metabolic syndrome.</p> |
| DOI | 10.1016/j.cmet.2016.03.012 |
| Alternate Journal | Cell Metab |
| PubMed ID | 27076071 |