Hartman Institute for Therapeutic Organ Regeneration

Publications

Found 104 results
Author Title Type [ Year(Asc)]
Filters: Keyword is Cell Differentiation  [Clear All Filters]
2023
Zhong L, Gordillo M, Wang X, Qin Y, Huang Y, Soshnev A, Kumar R, Nanjangud G, James D, C Allis D et al..  2023.  Dual role of lipids for genome stability and pluripotency facilitates full potency of mouse embryonic stem cells.. Protein Cell. 14(8):591-602.
Stamateris RE, Landa-Galvan HV, Sharma RB, Darko C, Redmond D, Rane SG, Alonso LC.  2023.  Noncanonical CDK4 signaling rescues diabetes in a mouse model by promoting β cell differentiation.. J Clin Invest. 133(18)
Luo Y, Yamada M, N'Tumba-Byn T, Asif H, Gao M, Hu Y, Marangoni P, Liu Y, Evans T, Rafii S et al..  2023.  SPRY4-dependent ERK negative feedback demarcates functional adult stem cells in the male mouse germline†.. Biol Reprod. 109(4):533-551.
2022
Schad SE, Chow A, Mangarin L, Pan H, Zhang J, Ceglia N, Caushi JX, Malandro N, Zappasodi R, Gigoux M et al..  2022.  Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions.. J Exp Med. 219(6)
2021
Gomez-Salinero JM, Itkin T, Rafii S.  2021.  Developmental angiocrine diversification of endothelial cells for organotypic regeneration.. Dev Cell. 56(22):3042-3051.
Howell ED, Yzaguirre AD, Gao P, Lis R, He B, Lakadamyali M, Rafii S, Tan K, Speck NA.  2021.  Efficient hemogenic endothelial cell specification by RUNX1 is dependent on baseline chromatin accessibility of RUNX1-regulated TGFβ target genes.. Genes Dev. 35(21-22):1475-1489.
Dignum T, Varnum-Finney B, Srivatsan SR, Dozono S, Waltner O, Heck AM, Ishida T, Nourigat-McKay C, Jackson DL, Rafii S et al..  2021.  Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo.. Cell Rep. 36(11):109675.
J Vandana J, Lacko LA, Chen S.  2021.  Phenotypic technologies in stem cell biology.. Cell Chem Biol. 28(3):257-270.
Lu TM, Houghton S, Magdeldin T, Durán JGabriel Ba, Minotti AP, Snead A, Sproul A, Nguyen D-HT, Xiang J, Fine HA et al..  2021.  Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate.. Proc Natl Acad Sci U S A. 118(8)
Zhao H, Huang X, Liu Z, Pu W, Lv Z, He L, Li Y, Zhou Q, Lui KO, Zhou B.  2021.  Pre-existing beta cells but not progenitors contribute to new beta cells in the adult pancreas.. Nat Metab. 3(3):352-365.
Cook B, Walker N, Zhang Q, Chen S, Evans T.  2021.  The small molecule DIPQUO promotes osteogenic differentiation via inhibition of glycogen synthase kinase 3-beta signaling.. J Biol Chem. 296:100696.
Lan Y, Banks KM, Pan H, Verma N, Dixon GR, Zhou T, Ding B, Elemento O, Chen S, Huangfu D et al..  2021.  Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation.. Cell Rep. 37(10):110095.
2020
Tsai S-Y, Ghazizadeh Z, Wang H-J, Amin S, Ortega FA, Badieyan ZSadat, Hsu Z-T, Gordillo M, Kumar R, Christini DJ et al..  2020.  A human embryonic stem cell reporter line for monitoring chemical-induced cardiotoxicity.. Cardiovasc Res. 116(3):658-670.
Sleiman Y, Souidi M, Kumar R, Yang E, Jaffré F, Zhou T, Bernardin A, Reiken S, Cazorla O, Kajava AV et al..  2020.  Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes.. EBioMedicine. 60:103024.
Cederquist GY, Tchieu J, Callahan SJ, Ramnarine K, Ryan S, Zhang C, Rittenhouse C, Zeltner N, Chung SYoung, Zhou T et al..  2020.  A Multiplex Human Pluripotent Stem Cell Platform Defines Molecular and Functional Subclasses of Autism-Related Genes.. Cell Stem Cell. 27(1):35-49.e6.
2019
Cook B, Rafiq R, Lee H, Banks KM, El-Debs M, Chiaravalli J, J Glickman F, Das BC, Chen S, Evans T.  2019.  Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-β.. Cell Chem Biol. 26(7):926-935.e6.
Li QV, Dixon G, Verma N, Rosen BP, Gordillo M, Luo R, Xu C, Wang Q, Soh C-L, Yang D et al..  2019.  Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation.. Nat Genet. 51(6):999-1010.
Durán JGabriel Ba, Lis R, Rafii S.  2019.  Haematopoietic stem cell reprogramming and the hope for a universal blood product.. FEBS Lett. 593(23):3253-3265.
2018
Xu B, Cai L, Butler JM, Chen D, Lu X, Allison DF, Lu R, Rafii S, Parker JS, Zheng D et al..  2018.  The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells.. Stem Cell Reports. 10(3):675-683.
Mukherjee S, Zhang T, Lacko LA, Tan L, Xiang JZhaoying, Butler JM, Chen S.  2018.  Derivation and characterization of a UCP1 reporter human ES cell line.. Stem Cell Res. 30:12-21.
Amin S, Cook B, Zhou T, Ghazizadeh Z, Lis R, Zhang T, Khalaj M, Crespo M, Perera M, Xiang JZhaoying et al..  2018.  Discovery of a drug candidate for GLIS3-associated diabetes.. Nat Commun. 9(1):2681.
Zhou T, Kim TWan, Chong CNok, Tan L, Amin S, Badieyan ZSadat, Mukherjee S, Ghazizadeh Z, Zeng H, Guo M et al..  2018.  A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival.. Nat Commun. 9(1):4815.
Durán JGabriel Ba, Lis R, Lu TM, Rafii S.  2018.  In vitro conversion of adult murine endothelial cells to hematopoietic stem cells.. Nat Protoc. 13(12):2758-2780.
Finley LWS, Vardhana SA, Carey BW, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S et al..  2018.  Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.. Nat Cell Biol. 20(5):565-574.
Ghazizadeh Z, Fattahi F, Mirzaei M, Bayersaikhan D, Lee J, Chae S, Hwang D, Byun K, Tabar MSharifi, Taleahmad S et al..  2018.  Prospective Isolation of ISL1 Cardiac Progenitors from Human ESCs for Myocardial Infarction Therapy.. Stem Cell Reports. 10(3):848-859.