Hartman Institute for Therapeutic Organ Regeneration

Publications

Found 117 results
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2023
Rubio-Navarro A, Gómez-Banoy N, Stoll L, Dündar F, Mawla AM, Ma L, Cortada E, Zumbo P, Li A, Reiterer M et al..  2023.  A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes.. Nat Cell Biol. 25(4):565-578.
Zhong L, Gordillo M, Wang X, Qin Y, Huang Y, Soshnev A, Kumar R, Nanjangud G, James D, C Allis D et al..  2023.  Dual role of lipids for genome stability and pluripotency facilitates full potency of mouse embryonic stem cells.. Protein Cell. 14(8):591-602.
Xue D, Narisu N, D Taylor L, Zhang M, Grenko C, Taylor HJ, Yan T, Tang X, Sinha N, Zhu J et al..  2023.  Functional interrogation of twenty type 2 diabetes-associated genes using isogenic hESC-derived β-like cells.. bioRxiv.
Lee D, Le Pen J, Yatim A, Dong B, Aquino Y, Ogishi M, Pescarmona R, Talouarn E, Rinchai D, Zhang P et al..  2023.  Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.. Science. 379(6632):eabo3627.
Lee D, Le Pen J, Yatim A, Dong B, Aquino Y, Ogishi M, Pescarmona R, Talouarn E, Rinchai D, Zhang P et al..  2023.  Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.. Science. 379(6632):eabo3627.
Yang L, Han Y, Zhou T, Lacko LA, Saeed M, Tan C, Danziger R, Zhu J, Zhao Z, Cahir C et al..  2023.  Isogenic human trophectoderm cells demonstrate the role of and associated variants in ZIKV infection.. iScience. 26(7):107001.
Yang L, Han Y, Zhou T, Lacko LA, Saeed M, Tan C, Danziger R, Zhu J, Zhao Z, Cahir C et al..  2023.  Isogenic human trophectoderm cells demonstrate the role of and associated variants in ZIKV infection.. iScience. 26(7):107001.
Elosegui-Artola A, Gupta A, Najibi AJ, Seo BRi, Garry R, Tringides CM, de Lázaro I, Darnell M, Gu W, Zhou Q et al..  2023.  Matrix viscoelasticity controls spatiotemporal tissue organization.. Nat Mater. 22(1):117-127.
Hudaiberdiev S, D Taylor L, Song W, Narisu N, Bhuiyan RM, Taylor HJ, Tang X, Yan T, Swift AJ, Bonnycastle LL et al..  2023.  Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits.. Proc Natl Acad Sci U S A. 120(35):e2206612120.
Tang X, Xue D, Zhang T, Nilsson-Payant BE, Carrau L, Duan X, Gordillo M, Tan AY, Qiu Y, Xiang J et al..  2023.  A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection.. Nat Cell Biol. 25(3):381-389.
Kubala JM, Laursen KB, Schreiner R, Williams RM, van der Mijn JC, Crowley MJ, Mongan NP, Nanus DM, Heller DA, Gudas LJ.  2023.  NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma.. Cancer Biol Ther. 24(1):2170669.
Luo Y, Yamada M, N'Tumba-Byn T, Asif H, Gao M, Hu Y, Marangoni P, Liu Y, Evans T, Rafii S et al..  2023.  SPRY4-dependent ERK negative feedback demarcates functional adult stem cells in the male mouse germline†.. Biol Reprod. 109(4):533-551.
Hirschhorn D, Budhu S, Kraehenbuehl L, Gigoux M, Schröder D, Chow A, Ricca JM, Gasmi B, De Henau O, Mangarin LMark B et al..  2023.  T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants.. Cell. 186(7):1432-1447.e17.
2022
Das BC, Nandwana NK, Das S, Nandwana V, Shareef MAdil, Das Y, Saito M, Weiss LM, Almaguel F, Hosmane NS et al..  2022.  Boron Chemicals in Drug Discovery and Development: Synthesis and Medicinal Perspective.. Molecules. 27(9)
Das BC, Nandwana NK, Das S, Nandwana V, Shareef MAdil, Das Y, Saito M, Weiss LM, Almaguel F, Hosmane NS et al..  2022.  Boron Chemicals in Drug Discovery and Development: Synthesis and Medicinal Perspective.. Molecules. 27(9)
Page DB, Beal K, Linch SN, Spinelli KJ, Rodine M, Halpenny D, Modi S, Patil S, Young RJ, Kaley T et al..  2022.  Brain radiotherapy, tremelimumab-mediated CTLA-4-directed blockade +/- trastuzumab in patients with breast cancer brain metastases.. NPJ Breast Cancer. 8(1):50.
Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai S-Y, Khalaj M, Zhou T, Samuel RM et al..  2022.  A dual knockin hESC reporter line for derivation of human SAN-like cells.. iScience. 25(4):104153.
Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai S-Y, Khalaj M, Zhou T, Samuel RM et al..  2022.  A dual knockin hESC reporter line for derivation of human SAN-like cells.. iScience. 25(4):104153.
Bram Y, Duan X, Nilsson-Payant BE, Chandar V, Wu H, Shore D, Fajardo A, Sinha S, Hassan N, Weinstein H et al..  2022.  Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path.. ACS Bio Med Chem Au. 2(6):627-641.
Hadland B, Varnum-Finney B, Dozono S, Dignum T, Nourigat-McKay C, Heck AM, Ishida T, Jackson DL, Itkin T, Butler JM et al..  2022.  Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics.. Nat Commun. 13(1):1584.
Yaron TM, Heaton BE, Levy TM, Johnson JL, Jordan TX, Cohen BM, Kerelsky A, Lin T-Y, Liberatore KM, Bulaon DK et al..  2022.  Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.. Sci Signal. 15(757):eabm0808.
Han Y, Tan L, Zhou T, Yang L, Carrau L, Lacko LA, Saeed M, Zhu J, Zhao Z, Nilsson-Payant BE et al..  2022.  A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.. Cell Stem Cell. 29(10):1475-1490.e6.
Han Y, Tan L, Zhou T, Yang L, Carrau L, Lacko LA, Saeed M, Zhu J, Zhao Z, Nilsson-Payant BE et al..  2022.  A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.. Cell Stem Cell. 29(10):1475-1490.e6.
Han Y, Tan L, Zhou T, Yang L, Carrau L, Lacko LA, Saeed M, Zhu J, Zhao Z, Nilsson-Payant BE et al..  2022.  A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.. Cell Stem Cell. 29(10):1475-1490.e6.
Han Y, Tan L, Zhou T, Yang L, Carrau L, Lacko LA, Saeed M, Zhu J, Zhao Z, Nilsson-Payant BE et al..  2022.  A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.. Cell Stem Cell. 29(10):1475-1490.e6.