Hartman Institute for Therapeutic Organ Regeneration
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2017
Cao Z, Scandura JM, Inghirami GG, Shido K, Ding B-S, Rafii S.  2017.  Molecular Checkpoint Decisions Made by Subverted Vascular Niche Transform Indolent Tumor Cells into Chemoresistant Cancer Stem Cells.. Cancer Cell. 31(1):110-126.
Gomez-Salinero JMaria, Rafii S.  2017.  Plasmin regulation of acute cytokine storm.. Blood. 130(1):5-6.
Shido K, Chavez D, Cao Z, Ko J, Rafii S, Ding B-S.  2017.  Platelets prime hematopoietic and vascular niche to drive angiocrine-mediated liver regeneration.. Signal Transduct Target Ther. 2:16044-.
Tripathi P, Rodriguez-Muela N, Klim JR, A de Boer S, Agrawal S, Sandoe J, Lopes CS, Ogliari KSassi, Williams LA, Shear M et al..  2017.  Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1.. Stem Cell Reports. 9(2):667-680.
Zhou Q.  2017.  Regenerative medicine: Interspecies pancreas transplants.. Nature. 542(7640):168-169.
Cavelti-Weder C, Zumsteg A, Li W, Zhou Q.  2017.  Reprogramming of Pancreatic Acinar Cells to Functional Beta Cells by In Vivo Transduction of a Polycistronic Construct Containing Pdx1, Ngn3, MafA in Mice.. Curr Protoc Stem Cell Biol. 40:4A.10.1-4A.10.12.
Ghazizadeh Z, Kao D-I, Amin S, Cook B, Rao S, Zhou T, Zhang T, Xiang Z, Kenyon R, Kaymakcalan O et al..  2017.  ROCKII inhibition promotes the maturation of human pancreatic beta-like cells.. Nat Commun. 8(1):298.
Abdel-Naby W, Cole B, Liu A, Liu J, Wan P, Guaiquil VH, Schreiner R, Infanger D, Lawrence BD, Rosenblatt MI.  2017.  Silk-Derived Protein Enhances Corneal Epithelial Migration, Adhesion, and Proliferation.. Invest Ophthalmol Vis Sci. 58(3):1425-1433.
Schachterle W, Badwe CR, Palikuqi B, Kunar B, Ginsberg M, Lis R, Yokoyama M, Elemento O, Scandura JM, Rafii S.  2017.  Sox17 drives functional engraftment of endothelium converted from non-vascular cells.. Nat Commun. 8:13963.
Cao Z, Ye T, Sun Y, Ji G, Shido K, Chen Y, Luo L, Na F, Li X, Huang Z et al..  2017.  Targeting the vascular and perivascular niches as a regenerative therapy for lung and liver fibrosis.. Sci Transl Med. 9(405)
Abdel-Naby W, Cole B, Liu A, Liu J, Wan P, Schreiner R, Infanger DW, Paulson NB, Lawrence BD, Rosenblatt MI.  2017.  Treatment with solubilized Silk-Derived Protein (SDP) enhances rabbit corneal epithelial wound healing.. PLoS One. 12(11):e0188154.
Guo M, Zhang T, Dong X, Xiang JZhaoying, Lei M, Evans T, Graumann J, Chen S.  2017.  Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E.. Cell Rep. 19(8):1512-1521.
2016
Atapattu L, Saha N, Chheang C, Eissman MF, Xu K, Vail ME, Hii L, Llerena C, Liu Z, Horvay K et al..  2016.  An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.. J Exp Med. 213(9):1741-57.
Chaudhary N, Gonzalez E, Chang S-H, Geng F, Rafii S, Altorki NK, McGraw TE.  2016.  Adenovirus Protein E4-ORF1 Activation of PI3 Kinase Reveals Differential Regulation of Downstream Effector Pathways in Adipocytes.. Cell Rep. 17(12):3305-3318.
Rafii S, Butler JM, Ding B-S.  2016.  Angiocrine functions of organ-specific endothelial cells.. Nature. 529(7586):316-25.
Page DB, Yuan J, Redmond D, Y Wen H, Durack JC, Emerson R, Solomon S, Dong Z, Wong P, Comstock C et al..  2016.  Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy.. Cancer Immunol Res. 4(10):835-844.
Fattahi F, Steinbeck JA, Kriks S, Tchieu J, Zimmer B, Kishinevsky S, Zeltner N, Mica Y, El-Nachef W, Zhao H et al..  2016.  Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease.. Nature. 531(7592):105-9.
Feng L, Cook B, Tsai S-Y, Zhou T, LaFlamme B, Evans T, Chen S.  2016.  Discovery of a Small-Molecule BMP Sensitizer for Human Embryonic Stem Cell Differentiation.. Cell Rep. 15(9):2063-75.
Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG et al..  2016.  Distinct bone marrow blood vessels differentially regulate haematopoiesis.. Nature. 532(7599):323-8.
Ma J, Nie K, Redmond D, Liu Y, Elemento O, Knowles DM, Tam W.  2016.  EBV-miR-BHRF1-2 targets PRDM1/Blimp1: potential role in EBV lymphomagenesis.. Leukemia. 30(3):594-604.
Poulos MG, Ramalingam P, Gutkin MC, Kleppe M, Ginsberg M, Crowley MJP, Elemento O, Levine RL, Rafii S, Kitajewski J et al..  2016.  Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis.. Nat Commun. 7:13829.
Liu Y, Giannopoulou EG, Wen D, Falciatori I, Elemento O, C Allis D, Rafii S, Seandel M.  2016.  Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells.. Nat Commun. 7:11275.
Bay AEPerez, Schreiner R, Benedicto I, Marzolo MPaz, Banfelder J, Weinstein AM, Rodriguez-Boulan EJ.  2016.  The fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells.. Nat Commun. 7:11550.
Ding B-S, Liu CH, Sun Y, Chen Y, Swendeman SL, Jung B, Chavez D, Cao Z, Christoffersen C, Nielsen LBo et al..  2016.  HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P) promotes regeneration and suppresses fibrosis in the liver.. JCI Insight. 1(21):e87058.
Cavelti-Weder C, Li W, Zumsteg A, Stemann-Andersen M, Zhang Y, Yamada T, Wang M, Lu J, Jermendy A, Bee YMong et al..  2016.  Hyperglycaemia attenuates in vivo reprogramming of pancreatic exocrine cells to beta cells in mice.. Diabetologia. 59(3):522-32.