Title | Maladapted endothelial cells flip the mesenchymal switch. |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | James D, Rafii S |
Journal | Sci Transl Med |
Volume | 6 |
Issue | 227 |
Pagination | 227fs12 |
Date Published | 2014 Mar 12 |
ISSN | 1946-6242 |
Keywords | Animals, Cell Transdifferentiation, Endothelial Cells, Humans, Mesoderm, Signal Transduction, Transforming Growth Factor beta, Veins |
Abstract | <p>Endothelial cells in the neointima undergo a transition to the mesenchymal phenotype, suggesting a therapeutic target for vein graft restenosis (Cooley et al., this issue).</p> |
DOI | 10.1126/scitranslmed.3008623 |
Alternate Journal | Sci Transl Med |
PubMed ID | 24622512 |