Title | It takes 2 to thrombopoies in the vascular niche. |
Publication Type | Journal Article |
Year of Publication | 2012 |
Authors | Gars E, Rafii S |
Journal | Blood |
Volume | 120 |
Issue | 14 |
Pagination | 2775-6 |
Date Published | 2012 Oct 04 |
ISSN | 1528-0020 |
Keywords | Animals, Blood Platelets, Female, Megakaryocytes, Placenta Growth Factor, Pregnancy Proteins, Receptors, CXCR4, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factor Receptor-1, Vascular Endothelial Growth Factor Receptor-2 |
Abstract | <p>In this issue of Blood, Pitchford et al demonstrate that intravenous administration of VEGF-A promotes megakaryocyte (Mk) maturation and localization to bone marrow sinusoidal endothelial cells (BMECs), stimulating thrombopoiesis.</p> |
DOI | 10.1182/blood-2012-07-435172 |
Alternate Journal | Blood |
PubMed ID | 23043022 |
Grant List | / / Howard Hughes Medical Institute / United States |