| Title | Inflammation joins the "niche". |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Peinado H, Rafii S, Lyden D |
| Journal | Cancer Cell |
| Volume | 14 |
| Issue | 5 |
| Pagination | 347-9 |
| Date Published | 2008 Nov 04 |
| ISSN | 1878-3686 |
| Keywords | Animals, Biomarkers, Tumor, Humans, Inflammation, Lung Neoplasms, Myeloid Cells, Signal Transduction |
| Abstract | <p>Bone marrow-derived cells have an important role in tumor metastasis and have been reported to "prime" distant tissues for tumor engraftment, although the mechanisms for their recruitment have remained unclear. A new study by Hiratsuka et al. describes an inflammatory signaling pathway that mediates the chemoattraction of myeloid and tumor cells to organ-specific metastatic sites.</p> |
| DOI | 10.1016/j.ccr.2008.10.012 |
| Alternate Journal | Cancer Cell |
| PubMed ID | 18977322 |
| PubMed Central ID | PMC2951628 |
| Grant List | / HHMI / Howard Hughes Medical Institute / United States |