Title | Does N-cadherin regulate interaction of hematopoietic stem cells with their niches? |
Publication Type | Journal Article |
Year of Publication | 2007 |
Authors | Hooper AT, Butler J, Petit I, Rafii S |
Journal | Cell Stem Cell |
Volume | 1 |
Issue | 2 |
Pagination | 127-9 |
Date Published | 2007 Aug 16 |
ISSN | 1875-9777 |
Keywords | Animals, Cadherins, Cell Adhesion, Hematopoietic Stem Cells, Mice, Osteoblasts |
Abstract | <p>In this issue of Cell Stem Cell, Kiel et al. (2007) demonstrate that N-cadherin is not expressed on repopulating hematopoietic stem cells (HSCs) and that reduction of osteoblasts does not affect HSC frequency, suggesting that other molecular pathways may also modulate the interaction of HSCs with their niches.</p> |
DOI | 10.1016/j.stem.2007.07.012 |
Alternate Journal | Cell Stem Cell |
PubMed ID | 18371341 |
PubMed Central ID | PMC2951616 |
Grant List | P01 HL059312-090006 / HL / NHLBI NIH HHS / United States P50 HL084936 / HL / NHLBI NIH HHS / United States P01 HL059312-100006 / HL / NHLBI NIH HHS / United States P50 HL084936-010003 / HL / NHLBI NIH HHS / United States P01 HL059312 / HL / NHLBI NIH HHS / United States P01 HL059312-080006 / HL / NHLBI NIH HHS / United States / HHMI / Howard Hughes Medical Institute / United States R21 HL083222-01 / HL / NHLBI NIH HHS / United States P01 HL067839-020004 / HL / NHLBI NIH HHS / United States R21 HL083222-02 / HL / NHLBI NIH HHS / United States P01 HL067839 / HL / NHLBI NIH HHS / United States P50 HL084936-030003 / HL / NHLBI NIH HHS / United States P01 HL059312-060006 / HL / NHLBI NIH HHS / United States P50 HL084936-020003 / HL / NHLBI NIH HHS / United States P01 HL067839-050004 / HL / NHLBI NIH HHS / United States P01 HL067839-030004 / HL / NHLBI NIH HHS / United States P01 HL059312-070006 / HL / NHLBI NIH HHS / United States P50 HL084936-040003 / HL / NHLBI NIH HHS / United States P01 HL067839-010004 / HL / NHLBI NIH HHS / United States P01 HL067839-040004 / HL / NHLBI NIH HHS / United States R21 HL083222 / HL / NHLBI NIH HHS / United States |